The show focuses equally on the relationships between Don Eppes, his brother Charlie Eppes and their father, Alan Eppes (Judd Hirsch), and on the brothers' efforts to fight crime, normally in Los Angeles. A typical episode begins with a crime, which is subsequently investigated by a team of FBI agents led by Don and mathematically described by Charlie, with the help of Larry Fleinhardt (Peter MacNicol) and/or Amita Ramanujan (Navi Rawat). The insights provided by Charlie's mathematics are always in some way crucial to solving the crime.
內容是描述Rob Morrow扮演的是一名洛杉機FBI探員和他那具備超乎常人數學天才的弟弟Charlie一起偵破了在洛杉機發生的大範圍嚴重罪案。Charlie對案件獨特的思考方式讓Don的同僚Terry Lake 和David Sinclair 都感到十分驚訝。與此同時,Don和Charlie的父親對於兩個兒子專注執著的個性會否使彼此在工作中產生摩擦感到擔心。Larry Fleinhardt 是Charlie的學院導師,他希望Charlie專注於學術研究而不是浪費無謂的精力幫助警方破案。