Season 1:
Craft Lawrence, a 25 year old peddler travelling from town to town selling and buying various things to make a living during a period much like Europe in the Middle Ages. One night when stopped at the town of Pasroe, he finds in his wagon a 250 year old pagan wolf deity girl named Holo. She appears to be that of a 15 year old girl, except for a wolf tail and ears. She introduces herself as the town's goddess of harvest who has kept it blessed with good harvests of wheat for many years. Despite having the responsibility to watch over the town, she wants to go back to her homeland in the north called Yoitsu, she believes the people have already forsaken her anyway and that she has kept her promise to maintain the good harvests.
劳伦斯是个到处旅行靠贩卖一些小商品为生的商人。某日当他从沉浸在丰收喜悦中的帕斯洛村离开后却发现自己的运货马车中沉睡着一位长着狼耳和狼尾的少女。少女自称ヨイツ的贤狼,希望劳伦斯能够带她回到遥远的北方故乡。于是,狼女与商人的旅行故事由此展开。
Season 2:
Continuing where the first series left off, it follows Craft Lawrence a experienced traveling merchant and his sharp tongued wolf god companion Horo on their journey to return to Horo's home to the north called Yoitsu. A tender relationship has blossomed between the characters, as they make deals, travel between cities, encounter religious fanatics or vice versa and mostly just do what a traveling merchant has to do to get by.
从教会都市出发的商人罗伦斯与贤狼赫罗,为了收集赫罗的故乡约伊兹的情报,而来到了冬季有着大祭典的热闹城市库梅尔森。在这里两人与鱼商人阿玛蒂邂逅了,而且阿玛蒂对赫罗一见钟情,并迅速开始对她展开追求攻势。另一方面,罗伦斯却和赫罗之间的微妙感情却因此加深了误解。然后,罗伦斯和阿玛蒂又因为各自的生意被卷入了大骚动中。