Game Loving Mutou Yugi was given an ancient relic by his grandfather called the sennen (Thousand-Year) puzzle. He completed the puzzle and was possessed by the spirit of an ancient pharaoh. The Pharaoh has no memories of who he is or how he got in the puzzle to begin with. The Pharaoh looks out for Yugi and his friends and Yugi agrees to help the Pharaoh recover his lost memory and help him be put to rest so he can go on to the afterlife and finally leave Yugi's Body.
游戏是一个喜欢拼图和游戏的男孩,由于他天真、善良的性格,经常被同学欺负。一天,他砌好了从爷爷处得来的千年积木后,得到了黑暗力量。当他打开黑暗之门时,竟出现了另一个游戏。一直在玩游戏方面未尝败绩的游戏,某天与游戏天才,海马集团社长海马濑人,以大受欢迎的“魔法与巫术卡”决斗。经过两轮激战,游戏胜出,而海马则在决斗后受到惩罚,陷入昏睡状态。其后,创造“魔法与巫术卡”的天才游戏设计师柏伽索斯与游戏一样,拥有天年道具。他持有的是能够看透对手心思的“千年眼”,这道具赋予他“心灵透析”的力量。使他成为最强的决斗者。