Set in a fictional universe in the Universal Century 0079, The Principality of Zeon has declared independence from the Earth Federation, and subsequently launched a war of independence. The conflict has directly affected every continent on earth and nearly every space colony and lunar settlement. Zeon has the upper hand through their use of a new type of weapon, called humanoid mobile suits. A Zeon recon team disobeys mission orders and attacks an unfinished base called Side 7. Its citizens accidentally find the Federation's new weapon called the Gundam. The newly formed crew of refugees, with support from Earth Federation soldiers stationed aboard the MS carrier White Base set out to change the course of the One Year War. 以月球跟地球軌道周邊浮游著數百枚太空殖民地(殖民衛星)的宇宙世紀0079年為舞台,少年阿姆罗‧雷捲入了地球聯邦與發動太空殖民地獨立戰爭的吉恩公国SIDE 3(港译“自护公国”,台译“吉翁公国”SIDE 3)的戰火當中,在偶然間乘坐上聯邦軍最新開發的機動戰士:RX-78-2 GUNDAM,被認定為少見的「新人類」。本作品即是以阿姆罗為中心,描述阿姆罗跟著GUNDAM的母艦白色要塞White base,歷經種種困難而成長的故事。